Lead: Qasim Aziz
Professor of Neurogastroenterology
Director of the Wingate Institute
Neurogastroenterology is a discipline of gastroenterology, aimed at understanding the neuromuscular control of gastrointestinal function, with particular emphasis on brain-gut interactions. The Neurogastroenterology Group is a multidisciplinary collaboration of experts, both clinicians and scientists, including adult and paediatric neurogastroenterologists, GI pathologists, physiologists, psychologists and psychiatrists, surgeons, immunologists, neuroscientists, and physicists. They are working across the Blizard Institute, Barts and The London School of Medicine and Dentistry, and Barts Health NHS Trust to advance basic scientific study and translate this knowledge to enhance patient care.
There are four major areas of our research on the gastrointestinal system: pain, neurodegeneration and ageing, reflux, obesity and connective tissue, all addressed by the neurogastroenterology group. The activities of the group span the disciplines of Gastroenterology, Gastrointestinal surgery, Psychiatry, Pharmacology, Neuroscience, Neurology, Immunology, Nutrition and Endocrinology. Many of our members are specialists in one or more of these areas and/or disciplines. The approaches comprise Molecular and Cellular, Experimental and Translational, and Population-based medicine, providing a vertical and horizontal matrix between our research themes. Our many collaborations clearly demonstrate the high level of national and international outreach. Our publication record emphasises our multidisciplinary approach. We provide state-of-the-art research facilities that promote sharing of resources within the campus. We have both individual and collective projects addressing four levels of investigation in each programme.
The four levels are:
- Fundamental research on function of human sensorimotor cells and systems
- Understanding disease in humans
- New diagnostics, therapies and personalized medicine
- Health service delivery and dissemination