My research focuses on the molecular and cellular mechanisms underlying muscular dystrophies. Briefly, muscular dystrophies are a group of inherited neuromuscular disorders characterised by progressive muscle degeneration, which may be associated neurological and cardiac defects. Currently there is no effective treatment. We are interested in developing cellular models for muscular dystrophies using the reprogramming and genome editing technologies to generate patient-specific induced pluripotent stem cell (iPSC) and isogenic control cells. Cellular models derived from isogenic pairs of iPSC provide an invaluable resource for studying disease pathogenesis and facilitating chemical and genetic screens.